Searching on the Go: The Effects of Fragmented Attention on Mobile Web Search Tasks

Smart phones and tablets are rapidly becoming our main method of accessing information and are frequently used to perform on-the-go search tasks. Mobile devices are commonly used in situations where attention must be divided, such as when walking down a street. Research suggests that this increases cognitive load and, therefore, may have an impact on performance. In this work we conducted a laboratory experiment with both device types in which we simulated everyday, common mobile situations that may cause fragmented attention, impact search performance and affect user perception. Our results showed that the fragmented attention induced by the simulated conditions significantly affected both participants' objective and perceived search performance, as well as how hurried they felt and how engaged they were in the tasks. Furthermore, the type of device used also impacted how users felt about the search tasks, how well they performed and the amount of time they spent engaged in the tasks. These novel insights provide useful information to inform the design of future interfaces for mobile search and give us a greater understanding of how context and device size affect search behaviour and user experience

Perceptions of the effect of fragmented attention on mobile web search tasks

Mobile devices are rapidly becoming our main method of accessing the Internet and are frequently used to perform on-the-go search tasks. The use of such devices in situations where attention must be divided, such as when walking, are common and research suggests that this increases cognitive load and, therefore, may have an impact on performance. In this work we conducted a laboratory experiment with both phone and tablet devices with the aim of evaluating common mobile situations that cause fragmented attention, impact search performance and impact on user perception. To do this the distraction level was varied by simulating 3 everyday situations: 1) walking quickly (on a treadmill), 2) navigating a pre-defined route and 3) sitting still which was used as the baseline condition). The results showed that different experimental conditions had a number of different effects on the participants' perceptions of their own search performance, how hurried they felt and how engaged they were in the tasks

Understanding Mobile Search Task Relevance and User Behaviour in Context

Improvements in mobile technologies have led to a dramatic change in how and when people access and use information, and is having a profound impact on how users address their daily information needs. Smart phones are rapidly becoming our main method of accessing information and are frequently used to perform `on-the-go' search tasks. As research into information retrieval continues to evolve, evaluating search behaviour in context is relatively new. Previous research has studied the effects of context through either self-reported diary studies or quantitative log analysis; however, neither approach is able to accurately capture context of use at the time of searching. In this study, we aim to gain a better understanding of task relevance and search behaviour via a task-based user study (n=31) employing a bespoke Android app. The app allowed us to accurately capture the user's context when completing tasks at different times of the day over the period of a week. Through analysis of the collected data, we gain a better understanding of how using smart phones on the go impacts search behaviour, search performance and task relevance and whether or not the actual context is an important factor.Comment: To appear in CHIIR 2019 in Glasgow, U

Equal pay as a precondition of justice?

Equality is typically presumed to be an end of justice; however, in this chapter, we argue that it is better understood as a condition of justice. Our argument draws on the Just World Fallacy, the phenomenon of people mistakenly believing fortuitous patterns of reward or harm to be reflective of justice. This phenomenon can undermine relationships of equality even where differences in reward or harm are ostensibly deserved. If everyone received equal pay, then the propensity for people to defer to the more successful or derogate the less successful would be diminished, and thus there would be greater scope for people to enter into the sorts of relationships of equal respect and regard that just communities require

Enhancing free-living fall risk assessment: Contextualising mobility based IMU data

Fall risk assessment needs contemporary approaches based on habitual data. Currently, inertial measurement unit (IMU) based wearables are used to inform free-living spatio-temporal gait characteristics to inform mobility assessment. Typically, a fluctuation of those characteristics will infer an increased fall risk. However, current approaches with IMU’s remains limited as there are no contextual data to comprehensively determine if underlying mechanistic (intrinsic) or envi-ronmental (extrinsic) factors impact mobility and therefore fall risk. Here, a case study is used to explore and discuss how contemporary video-based wearables could be used to supplement arising mobility-based IMU gait data to better inform habitual fall risk assessment. A single stroke survivor was recruited, and he conducted a series of mobility tasks in a lab and beyond while wearing video-based glasses and a single IMU. The latter generated topical gait characteristics that were discussed according to current research practices. Although current IMU-based approaches are beginning to provide habitual data they remain limited. Given the plethora of extrinsic factors that may influence mobility-based gait there is a need to corroborate IMU’s with video data to comprehensively inform fall risk assessment. Use of artificial intelligence (AI) based computer vision approaches could drastically aid the processing of video data in a timely and ethical manner. Many off-the-shelf AI tools exist to aid this current need and provide a means to automate con-textual analysis to better inform mobility from IMU gait data for an individualized and con-temporary approach to habitual fall risk assessment

Association of Variants at 1q32 and STAT3 with Ankylosing Spondylitis Suggests Genetic Overlap with Crohn's Disease

Ankylosing spondylitis (AS) is a common inflammatory arthritic condition. Overt inflammatory bowel disease (IBD) occurs in about 10% of AS patients, and in addition 70% of AS cases may have subclinical terminal ileitis. Spondyloarthritis is also common in IBD patients. We therefore tested Crohn's disease susceptibility genes for association with AS, aiming to identify pleiotropic genetic associations with both diseases. Genotyping was carried out using Sequenom and Applied Biosystems TaqMan and OpenArray technologies on 53 markers selected from 30 Crohn's disease associated genomic regions. We tested genotypes in a population of unrelated individual cases (n = 2,773) and controls (n = 2,215) of white European ancestry for association with AS. Statistical analysis was carried out using a Cochran-Armitage test for trend in PLINK. Strong association was detected at chr1q32 near KIF21B (rs11584383, P = 1.6×10−10, odds ratio (OR) = 0.74, 95% CI:0.68–0.82). Association with disease was also detected for 2 variants within STAT3 (rs6503695, P = 4.6×10−4. OR = 0.86 (95% CI:0.79–0.93); rs744166, P = 2.6×10−5, OR = 0.84 (95% CI:0.77–0.91)). Association was confirmed for IL23R (rs11465804, P = 1.2×10−5, OR = 0.65 (95% CI:0.54–0.79)), and further associations were detected for IL12B (rs10045431, P = 5.2×10−5, OR = 0.83 (95% CI:0.76–0.91)), CDKAL1 (rs6908425, P = 1.1×10−4, OR = 0.82 (95% CI:0.74–0.91)), LRRK2/MUC19 (rs11175593, P = 9.9×10−5, OR = 1.92 (95% CI: 1.38–2.67)), and chr13q14 (rs3764147, P = 5.9×10−4, OR = 1.19 (95% CI: 1.08–1.31)). Excluding cases with clinical IBD did not significantly affect these findings. This study identifies chr1q32 and STAT3 as ankylosing spondylitis susceptibility loci. It also further confirms association for IL23R and detects suggestive association with another 4 loci. STAT3 is a key signaling molecule within the Th17 lymphocyte differentiation pathway and further enhances the case for a major role of this T-lymphocyte subset in ankylosing spondylitis. Finally these findings suggest common aetiopathogenic pathways for AS and Crohn's disease and further highlight the involvement of common risk variants across multiple diseases

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

Context: Recent studies suggest that copy number variation in the human genome is extensive and may play an important role in susceptibility to disease, including neuropsychiatric disorders such as schizophrenia and autism. The possible involvement of copy number variants (CNVs) in bipolar disorder has received little attention to date. Objectives: To determine whether large (>100 000 base pairs) and rare (found in <1% of the population) CNVs are associated with susceptibility to bipolar disorder and to compare with findings in schizophrenia. Design: A genome-wide survey of large, rare CNVs in a case-control sample using a high-density microarray. Setting: The Wellcome Trust Case Control Consortium. Participants: There were 1697 cases of bipolar disorder and 2806 nonpsychiatric controls. All participants were white UK residents. Main Outcome Measures: Overall load of CNVs and presence of rare CNVs. Results: The burden of CNVs in bipolar disorder was not increased compared with controls and was significantly less than in schizophrenia cases. The CNVs previously implicated in the etiology of schizophrenia were not more common in cases with bipolar disorder. Conclusions: Schizophrenia and bipolar disorder differ with respect to CNV burden in general and association with specific CNVs in particular. Our data are consistent with the possibility that possession of large, rare deletions may modify the phenotype in those at risk of psychosis: those possessing such events are more likely to be diagnosed as having schizophrenia, and those without them are more likely to be diagnosed as having bipolar disorder

Investigating the genetic association between ERAP1 and ankylosing spondylitis

A strong association between ERAP1 and ankylosing spondylitis (AS) was recently identified by the Wellcome Trust Case Control Consortium and the Australo-Anglo-American Spondylitis Consortium (WTCCC-TASC) study. ERAP1 is highly polymorphic with strong linkage disequilibrium evident across the gene. We therefore conducted a series of experiments to try to identify the primary genetic association(s) with ERAP1. We replicated the original associations in an independent set of 730 patients and 1021 controls, resequenced ERAP1 to define the full extent of coding polymorphisms and tested all variants in additional association studies. The genetic association with ERAP1 was independently confirmed; the strongest association was with rs30187 in the replication set (P = 3.4 × 10−3). When the data were combined with the original WTCCC-TASC study the strongest association was with rs27044 (P = 1.1 × 10−9). We identified 33 sequence polymorphisms in ERAP1, including three novel and eight known non-synonymous polymorphisms. We report several new associations between AS and polymorphisms distributed across ERAP1 from the extended case–control study, the most significant of which was with rs27434 (P = 4.7 × 10−7). Regression analysis failed to identify a primary association clearly; we therefore used data from HapMap to impute genotypes for an additional 205 non-coding SNPs located within and adjacent to ERAP1. A number of highly significant associations (P < 5 × 10−9) were identified in regulatory sequences which are good candidates for causing susceptibility to AS, possibly by regulating ERAP1 expression

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis for which HLA-B*27 is the major genetic risk factor, although its role in the aetiology of AS remains elusive. To better understand the genetic basis of the MHC susceptibility loci, we genotyped 7,264 MHC SNPs in 22,647 AS cases and controls of European descent. We impute SNPs, classical HLA alleles and amino-acid residues within HLA proteins, and tested these for association to AS status. Here we show that in addition to effects due to HLA-B*27 alleles, several other HLA-B alleles also affect susceptibility. After controlling for the associated haplotypes in HLA-B, we observe independent associations with variants in the HLA-A, HLA-DPB1 and HLA-DRB1 loci. We also demonstrate that the ERAP1 SNP rs30187 association is not restricted only to carriers of HLA-B*27 but also found in HLA-B*40:01 carriers independently of HLA-B*27 genotype